Methylcobalamin - MB12
What does it involve?
Supplementing with vitamin B12 in the specific form of Methylcobalamin (MB12). One of the many tasks it does is to support/drive the 'Methlylation Cycle', the end product of which is raising levels of Glutathione. Gluathione is the substance the body uses to detoxify itself and has been shown to be consistently low in children with Autism and related disorders. Vitamin MB12 is poorly absorbed when taken orally, but can be helpful for some.
Dr James Neubrander pioneered the work on MB12 in children with Autism. He (any many others) believe that these children have, not only a deficiency, but a 'dependancy'. In this case the body requires a slow, steady and on-going delivery of the MB12. This can be achieved by using a higher dose compound, 25mg in 1ml making it viscous (thicker), and injecting it in small amounts (0.05 - 0.1ml), generally every 3 days, into the fatty area of the buttocks. The nature of the buttock fat, combined with the viscosity of the MB12 results in a slow on-going supplementation over a number of days. Adjustments in dosing frequency may be required for children with little or no 'butt' fat.
The syringes are very small, with short fine needles, the same ones used by those with Diabetes. Parents give them at home, very scarey at first but no problem once you get used to the idea!
How might it help?
James Neubrander Powerpoint Presentation from Autism One Conference 2005
(This is a Powerpoint presentation which takes a little while to load)
Further Reading & Resources
Methyl B12 - Myth, Masterpiece of Miracle ?
Excellent paper by Dr Neubrander
FREE On-line Video Explanation of Subcutaneous MB12 Injections
Dr James Neubrander on AutismMedia.org
Parents discuss side effects - FREE Video
Parents discuss being afraid of giving the injections - FREE VIDEO
Examples of administering injections - FREE VIDEO
PLEASE NOTE: MB12 injections are not yet widely available in the UK. At present they have to be imported from the US. Dr Neubrander is working with UK practitioners on ways to rectify this problem. We will bring you any news on this initiative as soon as we have it